Δ-9-tetrahydrocannabinol (THC) content in cannabis products, such as food supplements, vapes, or medicinal matrices, is strictly regulated in most countries worldwide. This has fueled demand for broad spectrum THC-free oil, and spurred interest in THC remediation technologies applicable at industrial scale level. Purification by chromatography is a fundamental laboratory process with diverse applications. Preparative liquid chromatography allows you to isolate compounds, increase the purity of an isolated relatively pure compound, fractionate complex mixtures, and more.
Single-Step Purification of THC, CBD, CBN, CBG and Minor Cannabinoids
CPC is recognized as the preferred technology for the purification of high quality Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) for the pharmaceutical and food supplement markets. The objective of this app note was to test the high selectivity of CPC and assess its capability to purify a set of key compounds (THC, CBD, CBN and CBG) and enrich several minor cannabinoids (CBDV, CBCV and CBC).
The VERITY CPC Lab System is a combination of the PLC 2050 and the CPC 250 for quick and automated purification of value molecules with high yields and purity at mg to g level. Among the different configurations, it can be connected to the VERITY® 1920 Mass Spectrometer online for a directed collection of your target compounds.
The VERITY CPC Pilot System combines the PLC 2500 Purification System with a CPC 1000 PRO for scaling up target compound purification. This system can be connect to external pump for stacked injection and unlimited automated production.
The VERITY® SKID LC is designed for use in preparative and industrial liquid chromatography (LC). The system automatically elutes the mobile phase, injects a solution, detects molecules by UV/VIS absorbance (by default 200 to 600 nm), and collects fractions when connected to a LC column, such as HPLC, MPLC, or CPC. Learn more about this system and request a quote below.
This ASPEC® system for positive pressure solid phase extraction (SPE) maximizes throughput by processing up to four samples in parallel. With its small footprint and multiple probes, it is the ideal choice for high-throughput SPE automation on 1, 3, or 6 mL cartridges. Combined with ASPEC SPE Cartridges, it generates reproducible and efficient sample cleanup for clinical, forensic, doping, food, and environmental testing labs.
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